Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study.

ABSTRACT:

Purpose

To determine clinical predictors associated with corticosteroid administration and its association with ICU mortality in critically ill patients with severe influenza pneumonia.

Methods

Secondary analysis of a prospective cohort study of critically ill patients with confirmed influenza pneumonia admitted to 148 ICUs in Spain between June 2009 and April 2014. Patients who received corticosteroid treatment for causes other than viral pneumonia (e.g., refractory septic shock and asthma or chronic obstructive pulmonary disease [COPD] exacerbation) were excluded. Patients with corticosteroid therapy were compared with those without corticosteroid therapy. We use a propensity score (PS) matching analysis to reduce confounding factors. The primary outcome was ICU mortality.

SUBMITTER: Moreno G 

PROVIDER: S-EPMC7095489 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature