Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia.

ABSTRACT:

Objective

To characterize behavior of 2-year-old children based on the severity of bronchopulmonary dysplasia (BPD).

Study design

We studied children born at 22-26 weeks of gestation and assessed at 22-26 months of corrected age with the Child Behavior Checklist (CBCL). BPD was classified by the level of respiratory support at 36 weeks of postmenstrual age. CBCL syndrome scales were the primary outcomes. The relationship between BPD grade and behavior was evaluated, adjusting for perinatal confounders. Mediation analysis was performed to evaluate whether cognitive, language, or motor skills mediated the effect of BPD grade on behavior.

Results

Of 2310 children, 1208 (52%) had no BPD, 806 (35%) had grade 1 BPD, 177 (8%) had grade 2 BPD, and 119 (5%) had grade 3 BPD. Wi

SUBMITTER: Brumbaugh JE 

PROVIDER: S-EPMC7096270 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature