Clinicopathological characteristics of histiocytic sarcoma affecting the central nervous system in dogs.

ABSTRACT:

Background

Histiocytic sarcoma affecting the central nervous system (CNS HS) in dogs may present as primary or disseminated disease, often characterized by inflammation. Prognosis is poor, and imaging differentiation from other CNS tumors can be problematic.

Objective

To characterize the clinicopathological inflammatory features, breed predisposition, and survival in dogs with CNS HS.

Animals

One hundred two dogs with HS, 62 dogs with meningioma.

Methods

Retrospective case series. Records were reviewed for results of cerebrospinal fluid (CSF) analysis, CBC, treatment, and outcome data.

Results

Predisposition for CNS HS was seen in Bernese Mountain Dogs, Golden Retrievers, Rottweilers, Corgis, and Shetland Sheepdogs (P ≤ .001). Corgis and Shetland Sheepdo

SUBMITTER: Toyoda I 

PROVIDER: S-EPMC7096655 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature