Role of multiheme cytochromes involved in extracellular anaerobic respiration in bacteria.
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ABSTRACT: Heme containing proteins are involved in a broad range of cellular functions, from oxygen sensing and transport to catalyzing oxidoreductive reactions. The two major types of cytochrome (b-type and c-type) only differ in their mechanism of heme attachment, but this has major implications for their cellular roles in both localization and mechanism. The b-type cytochromes are commonly cytoplasmic, or are within the cytoplasmic membrane, while c-type cytochromes are always found outside of the cytoplasm. The mechanism of heme attachment allows for complex c-type multiheme complexes, having the capacity to hold multiple electrons, to be assembled. These are increasingly being identified as secreted into the extracellular environment. For organisms that respire using extracellular substrates, t
SUBMITTER: Edwards MJ
PROVIDER: S-EPMC7096707 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
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