Gingivitis efficacy of a 0.454% w/w stannous fluoride dentifrice: a 24-week randomized controlled trial.

ABSTRACT:

Background

Plaque-induced gingivitis can be prevented and treated with regular effective oral hygiene, principally via mechanical cleaning with regular toothbrushing. To complement the mechanical plaque removal, antimicrobial ingredients can be incorporated into dentifrices to inhibit the growth of plaque. This study aimed to evaluate and compare gingivitis and the proportion of subjects moving between gingivitis severity (< 10, > 10 < 30, > 30% bleeding sites), and plaque reduction, following twice daily use of an experimental non-aqueous 0.454% weight/weight (w/w) stannous fluoride (SnF₂) dentifrice, compared to a negative control dentifrice over 12 and 24 weeks.

Method

This was a single-center, examiner-blinded, randomized, stratified, two-treatment arm, parall

SUBMITTER: Parkinson CR 

PROVIDER: S-EPMC7098169 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature