Hepatic alterations associated with fine particulate matter exposure.

ABSTRACT: Several studies have pointed to fine particulate matter (PM_2.5) as the main responsible for air pollution toxic effects. Indeed, PM_2.5 may not only cause respiratory and cardiovascular abnormalities but it may also affect other organs such as the liver. Be that as it may, only a few studies have evaluated the PM_2.5 effects on hepatic tissue. Moreover, most of them have not analyzed the relationship between particles composition and toxicological effects. In this study, healthy rats were subjected to urban levels of PM_2.5 particles in order to assess their structural and functional effects on the liver. During the exposure periods, mean PM_2.5 concentrations were slightly higher than the value suggested by the daily guideline of the Worl

SUBMITTER: Tavera Busso I 

PROVIDER: S-EPMC7099102 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature