HeMoQuest: a webserver for qualitative prediction of transient heme binding to protein motifs.

ABSTRACT:

Background

The notion of heme as a regulator of many physiological processes via transient binding to proteins is one that is recently being acknowledged. The broad spectrum of the effects of heme makes it important to identify further heme-regulated proteins to understand physiological and pathological processes. Moreover, several proteins were shown to be functionally regulated by interaction with heme, yet, for some of them the heme-binding site(s) remain unknown. The presented application HeMoQuest enables identification and qualitative evaluation of such heme-binding motifs from protein sequences.

Results

We present HeMoQuest, an online interface (http://bit.ly/hemoquest) to algorithms that provide the user with two distinct qualitative benefits. First, our implementati

SUBMITTER: Paul George AA 

PROVIDER: S-EPMC7099796 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature