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Factors associated with the development of septic shock in patients with candidemia: a post hoc analysis from two prospective cohorts.


ABSTRACT:

Background

Almost one third of the patients with candidemia develop septic shock. The understanding why some patients do and others do not develop septic shock is very limited. The objective of this study was to identify variables associated with septic shock development in a large population of patients with candidemia.

Methods

A post hoc analysis was performed on two prospective, multicenter cohort of patients with candidemia from 12 hospitals in Spain and Italy. All episodes occurring from September 2016 to February 2018 were analyzed to assess variables associated with septic shock development defined according to The Third International Consensus Definition for Sepsis and Septic Shock (Sepsis-3).

Results

Of 317 candidemic patients, 99 (31.2%) presented septic sho

SUBMITTER: Bassetti M 

PROVIDER: S-EPMC7099832 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature