Identification of Biomarkers for Osteosarcoma Based on Integration Strategy.
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ABSTRACT:
SUBMITTER: Bao J
PROVIDER: S-EPMC7101204 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Publications
Identification of Biomarkers for Osteosarcoma Based on Integration Strategy.
Bao Junjie J Song Zhaona Z Song Chunyu C Wang Yahui Y Li Wan W Mai Wei W Shi Qingyu Q Yu Hongwei H Ni Linying L Liu Yishu Y Lu Xiaolin X He Chuan C Chen Lina L Qu Guofan G
Medical science monitor : international medical journal of experimental and clinical research 20200316
BACKGROUND Osteosarcoma (OS) is the most common primary malignant tumor of bone. The identification of novel biomarkers is necessary for the diagnosis and treatment of osteosarcoma. MATERIAL AND METHODS We obtained 11 paired fresh-frozen OS samples and normal controls from patients between September 2015 and February 2017. We used an integration strategy that analyzes next-generation sequencing data by bioinformatics methods based on the pathogenesis of osteosarcoma. RESULTS One susceptibility l ...[more]
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