Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma.

ABSTRACT:

Importance

Coronavirus disease 2019 (COVID-19) is a pandemic with no specific therapeutic agents and substantial mortality. It is critical to find new treatments.

Objective

To determine whether convalescent plasma transfusion may be beneficial in the treatment of critically ill patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

Design, setting, and participants

Case series of 5 critically ill patients with laboratory-confirmed COVID-19 and acute respiratory distress syndrome (ARDS) who met the following criteria: severe pneumonia with rapid progression and continuously high viral load despite antiviral treatment; Pao2/Fio2 <300; and mechanical ventilation. All 5 were treated with convalescent plasma transfusion. The study was conduct

SUBMITTER: Shen C 

PROVIDER: S-EPMC7101507 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature