Liver Resection for Hepatocellular Carcinoma in Patients with Renal Dysfunction.

ABSTRACT:

Background

The aim of this study was to evaluate the feasibility of liver resection in hepatocellular carcinoma (HCC) patients with preoperative renal dysfunction (RD).

Methods

Data from 735 patients undergoing primary liver resection for HCC between 2002 and 2014 were analyzed. Short- and long-term outcomes were compared between the RD group, defined by a preoperative estimated glomerular filtration rate of <45 mL/min/1.73 m², and the non-RD group.

Results

Sixty-two patients had RD. The incidence of postoperative pleural effusion (24 vs. 11%; P = 0.007) and major complications (Clavien-Dindo III-V; 31 vs. 15%; P = 0.003) were significantly higher in RD patients. In RD patients with Child-Pugh A, 90-day mortality rate (1.9%) and median survival time (6.11 y

SUBMITTER: Shirata C 

PROVIDER: S-EPMC7101999 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature