Integrative omics of Lonicera japonica Thunb. Flower development unravels molecular changes regulating secondary metabolites.

ABSTRACT: Lonicera japonica Thunb. is an important medicinal plant. The secondary metabolites in L. japonica are diverse and vary in levels during development, leading to the ambiguous evaluation for its medical value. In order to reveal the regulatory mechanism of secondary metabolites during the flowering stages, transcriptomic, proteomic, and metabolomic analyses were performed. The integration analysis of omic-data illustrated that the metabolic changes over the flower developmental stages were mainly involved in sugar metabolism, lipopolysaccharide biosynthesis, carbon conversion, and secondary metabolism. Further proteomic analysis revealed that uniquely identified proteins were mainly involved in glycolysis/phenylpropanoids and tricarboxylic acid cycle/terpenoid backbone pathways in early and

SUBMITTER: Yang B 

PROVIDER: S-EPMC7102679 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature