Preoperative Prediction of Pathologic Response to Neoadjuvant Chemoradiotherapy in Patients With Esophageal Cancer Using ¹⁸F-FDG PET/CT and DW-MRI: A Prospective Multicenter Study.

ABSTRACT:

Purpose

Accurate preoperative prediction of pathologic response to neoadjuvant chemoradiotherapy (nCRT) in patients with esophageal cancer could enable omission of esophagectomy in patients with a pathologic complete response (pCR). This study aimed to evaluate the individual and combined value of ¹⁸F-fluorodeoxyglucose positron emission tomography with integrated computed tomography (¹⁸F-FDG PET/CT) and diffusion-weighted magnetic resonance imaging (DW-MRI) during and after nCRT to predict pathologic response in patients with esophageal cancer.

Methods and materials

In this multicenter prospective study, patients scheduled to receive nCRT followed by esophagectomy for esophageal cancer underwent ¹⁸F-FDG PET/CT and DW-MRI scanning before the

SUBMITTER: Borggreve AS 

PROVIDER: S-EPMC7103753 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature