Antiretroviral drug class and anaemia risk in the current treatment era among people living with HIV in the USA: a clinical cohort study.

ABSTRACT:

Objective

Anaemia is common among people living with HIV (PLWH) and has been associated with certain, often older, antiretroviral medications. Information on current antiretroviral therapy (ART) and anaemia is limited. The objective was to compare the associations between anaemia incidence or haemoglobin change with core ART classes in the current ART era.

Design

Retrospective cohort study.

Setting

USA-based prospective clinical cohort of PLWH aged 18 and above receiving care at eight sites between January 2010 and March 2018.

Participants

16 505 PLWH were included in this study.

Main outcome measures

Anaemia risk and haemoglobin change were estimated among PLWH for person-time on a protease inhibitor (PI) or an integrase strand transfer inhibitor (INSTI

SUBMITTER: Harding BN 

PROVIDER: S-EPMC7103836 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature