Statin use in asthmatics on inhaled corticosteroids is associated with decreased risk of emergency department visits.

ABSTRACT:

Objective

Statins are hypothesized to have beneficial effects in asthma management through their pleiotropic anti-inflammatory effects. Several studies have examined this relationship, but have yielded conflicting results. This study investigates the effect of statin use on asthma-related hospitalizations and/or emergency department (ED) visits, and whether this relationship varies by concomitant inhaled corticosteroid (ICS) in a large cohort of asthma patients.

Methods

Subjects with asthma, a recent history of asthma exacerbation, and who were 18 years or older were selected from the population-based Medco Health Solutions administrative database over a 1 year period. Prescription claims for statins and asthma medications, and asthma-related hospitalizations and/or ED visit

SUBMITTER: Tse SM 

PROVIDER: S-EPMC7105171 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature