Risk Factors Associated with Endometrial Pathology in Premenopausal Breast Cancer Patients Treated with Tamoxifen.

ABSTRACT:

Purpose

To evaluate factors associated with endometrial pathology during tamoxifen use in premenopausal breast cancer (BC) patients.

Materials and methods

We reviewed the medical records of premenopausal BC patients treated with tamoxifen who underwent endometrial biopsy with or without hysteroscopy. Clinical characteristics were compared between women with endometrial pathology (endometrial hyperplasia or cancer) and those with normal histology or endometrial polyps.

Results

Among 284 endometrial biopsies, endometrial hyperplasia was diagnosed in 7 patients (2.5%), endometrial cancer was diagnosed in 5 patients (1.8%), normal histology was noted in 146 patients (51.4%), and endometrial polyp was present in 114 patients (40.1%). When comparing women with endometrial c

SUBMITTER: Lee M 

PROVIDER: S-EPMC7105402 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature