Relationship Between Electrical Instability and Pumping Performance During Ventricular Tachyarrhythmia: Computational Study.

ABSTRACT: There are representative electrical parameters for understanding the mechanism of reentrant waves in studies on tachyarrhythmia, namely the action potential duration (APD), dominant frequency, phase singularity, and filament. However, there are no studies that have directly identified the correlation between these electrophysiological parameters and cardiac contractility. Therefore, we have identified individual and integrative correlations between these electrical phenomena and contractility during tachyarrhythmia by deriving regression equations and also investigated the electrophysiological parameters affecting cardiac contractility during tachyarrhythmia. We simulated ventricular tachyarrhythmia with 48 types of electrical patterns by applying four reentry generation methods and changi

SUBMITTER: Jeong DU 

PROVIDER: S-EPMC7105731 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature