Evaluation of the reentry vulnerability index to predict ventricular tachycardia circuits using high-density contact mapping.

ABSTRACT:

Background

Identifying arrhythmogenic sites to improve ventricular tachycardia (VT) ablation outcomes remains unresolved. The reentry vulnerability index (RVI) combines activation and repolarization timings to identify sites critical for reentrant arrhythmia initiation without inducing VT.

Objective

The purpose of this study was to provide the first assessment of RVI's capability to identify VT sites of origin using high-density contact mapping and comparison with other activation-repolarization markers of functional substrate.

Methods

Eighteen VT ablation patients (16 male; 72% ischemic) were studied. Unipolar electrograms were recorded during ventricular pacing and analyzed offline. Activation time (AT), activation-recovery interval (ARI), and repolarization time (R

SUBMITTER: Orini M 

PROVIDER: S-EPMC7105818 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature