Association of Sex With Severity of Coronary Artery Disease, Ischemia, and Symptom Burden in Patients With Moderate or Severe Ischemia: Secondary Analysis of the ISCHEMIA Randomized Clinical Trial.

ABSTRACT:

Importance

While many features of stable ischemic heart disease vary by sex, differences in ischemia, coronary anatomy, and symptoms by sex have not been investigated among patients with moderate or severe ischemia. The enrolled ISCHEMIA trial cohort that underwent coronary computed tomographic angiography (CCTA) was required to have obstructive coronary artery disease (CAD) for randomization.

Objective

To describe sex differences in stress testing, CCTA findings, and symptoms in ISCHEMIA trial participants.

Design, setting, and participants

This secondary analysis of the multicenter ISCHEMIA randomized clinical trial analyzed baseline characteristics of patients with stable ischemic heart disease. Individuals were enrolled from July 2012 to January 2018 based on loca

SUBMITTER: Reynolds HR 

PROVIDER: S-EPMC7105951 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature