Analysis of Bovine Tuberculosis Transmission in Jalisco, Mexico through Whole-genome Sequencing.

ABSTRACT:

Introduction

Bovine tuberculosis, caused by M. bovis, is endemic in Mexico and has had a big impact on public health. Jalisco is considered to be an important dairy region in the country, accounting for approximately 19% of the total milk production. Within Jalisco, the region of Altos Sur holds the largest proportion of the cattle inventory of the state.

Material and methods

To determine the frequency of bovine tuberculosis in Altos Sur, Jalisco, as well as M. bovis genetic diversity, sampling of tissue (lymph nodes, lungs, and liver) from Holstein cattle was performed in four abattoirs belonging to three municipalities of this region (Tepatitlán de Morelos, San Miguel el Alto, and Arandas). Spoligotyping and whole-genome sequencing were carried out to assess

SUBMITTER: Escarcega DAV 

PROVIDER: S-EPMC7105993 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature