Case fatality rate and viral aetiologies of acute respiratory tract infections in HIV positive and negative people in Africa: The VARIAFRICA-HIV systematic review and meta-analysis.

ABSTRACT:

Background

To set priorities for efficient control of acute respiratory tract infection (ARTI) in Africa, it is necessary to have accurate estimate of its burden, especially among HIV-infected populations.

Objectives

To compare case fatality rate (CFR) and viral aetiologies of ARTI between HIV-positive and HIV-negative populations in Africa.

Study design

We searched PubMed, EMBASE, Web of Knowledge, Africa Journal Online, and Global Index Medicus to identify studies published from January 2000 to April 2018. Random-effect meta-analysis method was used to assess association (pooled weighted odds ratios (OR) with 95% confidence interval (CI)).

Results

A total of 36 studies (126,526 participants) were included. CFR was significantly higher in patients with HIV tha

SUBMITTER: Kenmoe S 

PROVIDER: S-EPMC7106531 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature