How can gastro-intestinal tuberculosis diagnosis be improved? A prospective cohort study.

ABSTRACT:

Background

Gastrointestinal tuberculosis (TB) is diagnostically challenging; therefore, many cases are treated presumptively. We aimed to describe features and outcomes of gastrointestinal TB, determine whether a clinical algorithm could distinguish TB from non-TB diagnoses, and calculate accuracy of diagnostic tests.

Methods

We conducted a prospective cohort study of hospitalized patients in Kota Kinabalu, Malaysia, with suspected gastrointestinal TB. We recorded clinical and laboratory characteristics and outcomes. Tissue samples were submitted for histology, microscopy, culture and GeneXpert MTB/RIF®. Patients were followed for up to 2 years.

Results

Among 88 patients with suspected gastrointestinal TB, 69 were included in analyses; 52 (75%) had a final diagnosis o

SUBMITTER: Lowbridge C 

PROVIDER: S-EPMC7106693 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature