Change in glucose intolerance status and risk of incident cardiovascular disease: Tehran Lipid and Glucose Study.

ABSTRACT:

Background

To assess the impact of changes in different glucose tolerance states on risk of incident cardiovascular disease (CVD)/coronary heart disease (CHD).

Methods

A total of 4094 Iranians (43.9% men) aged ≥ 30 years, without diabetes and CVD at enrolment were included. The following categories were defined both at baseline visit and 3 years later (second visit): normal fasting glucose (NFG), normal glucose tolerance (NGT), NFG and NGT (NFG/NGT), impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and IFG and/or IGT (IFG/IGT). Changes in the categories, i.e. regression to normoglycemia, remaining in previous status and progression to diabetes were assessed. We used Cox's proportional hazard models adjusted for traditional risk factors and their changes, to e

SUBMITTER: Kabootari M 

PROVIDER: S-EPMC7106714 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature