Human bocavirus in children hospitalized for acute gastroenteritis: a case-control study.

ABSTRACT:

Background

Human bocavirus (HBoV) was recently discovered in children with respiratory tract disease and gastroenteritis. The causative role of HBoV in human gastroenteritis remains uncertain, and, to our knowledge, no previous case-control study has studied the relationship between HBoV and gastroenteritis.

Methods

We conducted a case-control study that examined stool samples from 397 children with diarrhea and from 115 asymptomatic control subjects. HBoV was detected using polymerase chain reaction. Real-time polymerase chain reaction was used to quantify the HBoV loads in case and control groups. Common enteric viruses were examined using enzyme-linked immunosorbent assays, polymerase chain reaction, and reverse-transcription polymerase chain reaction.

Results

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SUBMITTER: Cheng WX 

PROVIDER: S-EPMC7107984 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature