Clinical and Virological Characteristics of Acute Sinusitis in Children.

ABSTRACT:

Background

Acute bacterial sinusitis is a frequent complication of viral upper respiratory infection (URI). We describe the clinical and virologic features of URIs that remain uncomplicated and those that precede an episode of sinusitis. We hypothesize that certain viruses are more likely to lead to acute sinusitis, and we compare viruses identified at the time of diagnosis of sinusitis with those identified early in the URI.

Methods

Children aged 48-96 months were followed longitudinally for 1 year. Nasal samples were obtained at surveillance visits, on Day 3-4 of the URI, and on Day 10, when sinusitis was diagnosed. Molecular diagnostic testing was performed on nasal washes for common respiratory viruses and pathogenic bacteria. A standardized score was used to quantify sy

SUBMITTER: DeMuri GP 

PROVIDER: S-EPMC7108184 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature