Ontology highlight
ABSTRACT:
SUBMITTER: Ansell SM
PROVIDER: S-EPMC7108914 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
The Journal of clinical investigation 20200401 4
Lymphoid malignancies typically promote an infiltrate of immune cells at sites involved by the disease. While some of the immune cells present in lymphoma have effector function, the immune system is unable to eradicate the malignant clone. Therapies that optimize immune function therefore have the potential to improve the outcome of lymphoma patients. In this Review, we discuss immunologic approaches that directly target the malignant cell as well as approaches to optimize both the innate and a ...[more]