MRI-based radiomics model for preoperative prediction of 5-year survival in patients with hepatocellular carcinoma.

ABSTRACT:

Background

Recurrence is the major cause of mortality in patients with resected HCC. However, without a standard approach to evaluate prognosis, it is difficult to select candidates for additional therapy.

Methods

A total of 201 patients with HCC who were followed up for at least 5 years after curative hepatectomy were enrolled in this retrospective, multicentre study. A total of 3144 radiomics features were extracted from preoperative MRI. The random forest method was used for radiomics signature building, and five-fold cross-validation was applied. A radiomics model incorporating the radiomics signature and clinical risk factors was developed.

Results

Patients were divided into survivor (n = 97) and non-survivor (n = 104) groups based on the 5-year survival after su

SUBMITTER: Wang XH 

PROVIDER: S-EPMC7109104 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature