Portable Microfluidic Biosensing System for Real-Time Analysis of Microdialysate in Transplant Kidneys.

ABSTRACT: Currently, there is a severe shortage of donor kidneys that are fit for transplantation, due in part to a lack of adequate viability assessment tools for transplant organs. This work presents the integration of a novel wireless two-channel amperometric potentiostat with microneedle-based glucose and lactate biosensors housed in a 3D printed chip to create a microfluidic biosensing system that is genuinely portable. The wireless potentiostat transmits data via Bluetooth to an Android app running on a tablet. The whole miniaturized system is fully enclosed and can be integrated with microdialysis to allow continuous monitoring of tissue metabolite levels in real time. We have also developed a wireless portable automated calibration platform so that biosensors can be calibrated away from the

SUBMITTER: Samper IC 

PROVIDER: S-EPMC7110273 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature