Unification of optimal targeting methods in transcranial electrical stimulation.

ABSTRACT: One of the major questions in high-density transcranial electrical stimulation (TES) is: given a region of interest (ROI) and electric current limits for safety, how much current should be delivered by each electrode for optimal targeting of the ROI? Several solutions, apparently unrelated, have been independently proposed depending on how "optimality" is defined and on how this optimization problem is stated mathematically. The least squares (LS), weighted LS (WLS), or reciprocity-based approaches are the simplest ones and have closed-form solutions. An extended optimization problem can be stated as follows: maximize the directional intensity at the ROI, limit the electric fields at the non-ROI, and constrain total injected current and current per electrode for safety. This problem requir

SUBMITTER: Fernandez-Corazza M 

PROVIDER: S-EPMC7110419 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature