Exposure to multiple air pollutants and the incidence of coronary heart disease: A fine-scale geographic analysis.

ABSTRACT: Geographical variations in cardiovascular disease rates have been linked to individual air pollutants. Investigating the relation between cardiovascular disease and exposure to a complex mixture of air pollutants requires holistic approaches. We assessed the relationship between exposure to multiple air pollutants and the incidence of coronary heart disease (CHD) in a general population sample. We collected data in the Lille MONICA registry (2008-2011) on 3268 incident cases (age range: 35-74). Based on 20 indicators, we derived a composite environmental score (SEnv) for cumulative exposure to air pollution. Poisson regression models were used to analyse associations between CHD rates on one hand and SEnv and each single indicator on the other (considered in tertiles, where T3 is the most

SUBMITTER: Occelli F 

PROVIDER: S-EPMC7112033 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature