Vitamin D and Atherosclerotic Cardiovascular Disease.

ABSTRACT:

Context

A large body of experimental and observational data has implicated vitamin D deficiency in the development of cardiovascular disease. However, evidence to support routine vitamin D supplementation to prevent or treat cardiovascular disease is lacking.

Design and results

A comprehensive literature review was performed using PubMed and other literature search engines. Mounting epidemiological evidence and data from Mendelian randomization studies support a link between vitamin D deficiency and adverse cardiovascular health outcomes, but randomized trial evidence to support vitamin D supplementation is sparse. Current public health guidelines restrict vitamin D intake recommendations to the maintenance of bone health and prevention of fractures. Two recently published l

SUBMITTER: Hiemstra TF 

PROVIDER: S-EPMC7112191 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature