Biologics in chronic rhinosinusitis with nasal polyposis.

ABSTRACT:

Objective

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common and heterogeneous inflammatory condition, for which the drivers of the underlying inflammation are not yet fully understood. The use of biologic therapies to target specifically relevant effector cells or cytokines in CRSwNP is a growing field of interest. The objectives of this review are to provide an update on the existing studies of biologics in CRSwNP and to identify potential future areas for further research.

Data sources

An initial literature review of biologic therapies in CRS was performed through publications gathered from a PubMed search for title/abstract containing "biologic" and "chronic rhinosinusitis." Further manuscripts describing scientific premise for each biologic were then reviewed

SUBMITTER: Laidlaw TM 

PROVIDER: S-EPMC7113089 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature