Changes in Disease Activity and Damage Over Time in Patients With Morphea.

ABSTRACT:

Importance

Prospective studies of the disease course in patients with morphea are lacking, particularly those comparing adults and children.

Objective

To investigate the disease course in patients with morphea treated with standard-of-care therapy using validated clinical outcome measures.

Design, setting, and participants

Prospective cohort study of 130 adults and children from the Morphea in Adults and Children cohort with at least 2 years of clinical follow-up and Localized Scleroderma Cutaneous Assessment Tool scores recorded at each study visit. Study patients were seen at a tertiary referral center (UT Southwestern Medical Center, Dallas, Texas) from November 1, 2008, through April 1, 2016. The dates of analysis were May 2016 through July 2019.

Exposures

SUBMITTER: O'Brien JC 

PROVIDER: S-EPMC7113826 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature