Polyethyleneimine-Stabilized Platinum Nanoparticles as Peroxidase Mimic for Colorimetric Detection of Glucose.

ABSTRACT: Colorimetric detection of glucose using enzyme-mimic nanoparticles (NPs) has been drawing great attention. However, many NPs lack good stability in solution, which results in reduced color change of substrates in colorimetric detection. Liner soluble macromolecules with high cationic density may be suitable candidates for the stabilization of NPs. Herein, we prepared polyethyleneimine-stabilized platinum NPs (Pt n -PEI NPs) for colorimetric detection of glucose. The platinum NPs (Pt NPs) used in this system had small size (from 3.21 to 3.70 nm) and narrow size distribution. Pt50-PEI NPs had high stability within one week with a hydrodynamic size of ∼25 nm and slightly positive zeta potential. Pt50-PEI NPs-catalyzed oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) in the presence of H2O2,

SUBMITTER: Cui Y 

PROVIDER: S-EPMC7114613 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature