Vector-based genetically modified vaccines: Exploiting Jenner's legacy.

ABSTRACT: The global vaccine market is diverse while facing a plethora of novel developments. Genetic modification (GM) techniques facilitate the design of 'smarter' vaccines. For many of the major infectious diseases of humans, like AIDS and malaria, but also for most human neoplastic disorders, still no vaccines are available. It may be speculated that novel GM technologies will significantly contribute to their development. While a promising number of studies is conducted on GM vaccines and GM vaccine technologies, the contribution of GM technology to newly introduced vaccines on the market is disappointingly limited. In this study, the field of vector-based GM vaccines is explored. Data on currently available, actually applied, and newly developed vectors is retrieved from various sources, synth

SUBMITTER: Ramezanpour B 

PROVIDER: S-EPMC7115478 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature