Parallelized Wireless Sensing System for Continuous Monitoring of Microtissue Spheroids.

ABSTRACT: Currently, the use of electrical readout methods for the investigation of microtissue spheroids in combination with lab automation tools is hindered by the cable connections that are required to interrogate the on-chip-integrated electrodes. To overcome this limitation, we developed a wireless sensor scheme, which can detect the size variation of microtissues during long-term culturing and drug exposure assays. The sensor system includes an interrogation board, which is composed of an inductor-capacitor (LC) readout circuit, and the tissue culture platform with integrated split-ring sensors. The magnetic coupling between the LC circuit and the sensors enables the interrogation of the on-chip sensors without any wire connection to the culture platform. By optimizing the sensor dimensions an

SUBMITTER: Dong L 

PROVIDER: S-EPMC7115843 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature