Ontology highlight
ABSTRACT: Background
The association between diet and head and neck cancer (HNC) survival is unclear.Methods
Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.Results
Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alcohol consumption (fully adjusted analyses), the association with survival disappeared for fruit (HR 0.91, 95% CI 0.67, 1.23; P for trend = .55) and attenuated for vegetables (HR 0.79, 95% CI 0.61, 1.03; P for trend = .04). We observed no association between survival and deep-fried food intake in minimally adjusted or fully adjusted analyses (HR 0.88 95% CI 0.72, 1.07; P for trend = .13).Conclusions
Vegetable intake and HNC survival are modestly associated. There is some confounding by tobacco and alcohol consumption.
SUBMITTER: Lang S
PROVIDER: S-EPMC7116031 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Lang Samantha S Schimansky Sarah S Beynon Rhona R Penfold Christopher C Davies Amy A Waylen Andrea A Thomas Steven S Pring Miranda M Pawlita Michael M Waterboer Tim T Ness Andrew R AR
Head & neck 20190130 7
<h4>Background</h4>The association between diet and head and neck cancer (HNC) survival is unclear.<h4>Methods</h4>Cox proportional hazard models measured the association between fruit, vegetable, and deep-fried food intake and HNC overall survival adjusting for clinical, social and lifestyle variables including smoking, alcohol, and HPV status.<h4>Results</h4>Fruit and vegetable intake and improved survival were associated in minimally adjusted analyses. Following adjustment for smoking and alc ...[more]