Dsuite - Fast D-statistics and related admixture evidence from VCF files.

ABSTRACT: Patterson's D, also known as the ABBA-BABA statistic, and related statistics such as the f₄ -ratio, are commonly used to assess evidence of gene flow between populations or closely related species. Currently available implementations often require custom file formats, implement only small subsets of the available statistics, and are impractical to evaluate all gene flow hypotheses across data sets with many populations or species due to computational inefficiencies. Here, we present a new software package Dsuite, an efficient implementation allowing genome scale calculations of the D and f₄ -ratio statistics across all combinations of tens or hundreds of populations or species directly from a variant call format (VCF) file. Our program also implements statistics suite

SUBMITTER: Malinsky M 

PROVIDER: S-EPMC7116594 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature