Association of maternal prenatal psychological stressors and distress with maternal and early infant faecal bacterial profile.

ABSTRACT:

Objective

Findings from animal studies indicate that the early gut bacteriome is a potential mechanism linking maternal prenatal stress with health trajectories in offspring. However, clinical studies are scarce and the associations of maternal psychological profiles with the early infant faecal bacteriome are unknown. This study aimed to investigate the associations of prenatal stressors and distress with early infant faecal bacterial profiles in a South African birth cohort study.

Methods

Associations between prenatal symptoms of depression, distress, intimate partner violence (IPV) and posttraumatic stress disorder (PTSD) and faecal bacterial profiles were evaluated in meconium and subsequent stool specimens from 84 mothers and 101 infants at birth, and longitudinally fro

SUBMITTER: Naude PJW 

PROVIDER: S-EPMC7116644 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature