Identification and molecular characterization of a novel serotype infectious bronchitis virus (GI-28) in China.

ABSTRACT: Avian infectious bronchitis coronavirus (IBV) is a major poultry pathogen. A characteristic feature of IBV is the occurrence of many different strains belonging to different serotypes, which renders complete control of the disease by vaccination a challenging task due to the poor cross-protection between different serotypes. In this study, based on the results of S1 sequence analysis and virus cross-neutralization tests, IBV strain ck/CH/LGX/111119 was found to be genetically and antigenically different from other known IBV types, representing not only a novel genotype, but also a novel serotype (designated as GI-28). Viruses belonging to this novel serotype have been isolated from several regions in China in recent years, suggesting endemic circulation of the serotype in various geographi

SUBMITTER: Chen Y 

PROVIDER: S-EPMC7117283 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature