Touching the Surface: Diverse Roles for the Flagellar Membrane in Kinetoplastid Parasites.

ABSTRACT: While flagella have been studied extensively as motility organelles, with a focus on internal structures such as the axoneme, more recent research has illuminated the roles of the flagellar surface in a variety of biological processes. Parasitic protists of the order Kinetoplastida, which include trypanosomes and Leishmania species, provide a paradigm for probing the role of flagella in host-microbe interactions and illustrate that this interface between the flagellar surface and the host is of paramount importance. An increasing body of knowledge indicates that the flagellar membrane serves a multitude of functions at this interface: attachment of parasites to tissues within insect vectors, close interactions with intracellular organelles of vertebrate cells, transactions between flagella

SUBMITTER: Kelly FD 

PROVIDER: S-EPMC7117551 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature