Dataset Information

Antibiotic resistance pattern of Staphylococcus aureus with reference to MRSA isolates from pediatric patients.

ABSTRACT:

Aim

The extent of methicillin-resistant Staphylococcus aureus (MRSA) infection in Nepalese children is largely unknown.

Materials & methods

Six hundred and seventy-two clinical samples collected from 232 patients between June and November 2016 were processed in a microbiology laboratory.

Results

Out of 300 culture-positive samples, 52 (17.3%) were S. aureus isolates. Among those 52, 39 (75.0%) were found to be MRSA. The infection rate of S. aureus was shown to be higher in inpatients (55.7%) compared with outpatients (44.3%) at p = 0.637, 95% CI. Thirteen types of antibiotics were used in the antibiotic susceptibility test. MRSA isolates showed 100 and 0% resistance to penicillin and vancomycin, respectively. The D-test showed inducible clindamycin-resistant phenotype in 15.4% of MRSA isolates.

Conclusion

This demonstrates the utmost need for routine testing for MRSA in Nepalese hospitals.

SUBMITTER: Gurung RR

PROVIDER: S-EPMC7117559 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Publications

Antibiotic resistance pattern of <i>Staphylococcus aureus</i> with reference to MRSA isolates from pediatric patients.

Gurung Raja Ram RR Maharjan Prashanna P Chhetri Ganga Gharti GG

Future science OA 20200224 4

<h4>Aim</h4>The extent of methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) infection in Nepalese children is largely unknown.<h4>Materials & methods</h4>Six hundred and seventy-two clinical samples collected from 232 patients between June and November 2016 were processed in a microbiology laboratory.<h4>Results</h4>Out of 300 culture-positive samples, 52 (17.3%) were <i>S. aureus</i> isolates. Among those 52, 39 (75.0%) were found to be MRSA. The infection rate of <i>S. aureus</i> was s ...[more]

PMID: 32257376

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