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Cell cycle progression data on human skin cancer cells with anticancer synthetic peptide LTX-315 treatment.


ABSTRACT: Skin cancer, including melanoma and non-melanoma (NMSC), represents the most common type of malignancy in the white population [1]. The incidence rate of melanoma is increasing worldwide, while the associated mortality remains stable. On the other hand, the incidence of NMSC varies widely [1,2]. Camilio and collaborators recently described the anticancer properties of LTX-315, a novel synthetic anticancer peptide, commercialized as Oncopore™ [3,4]. Despite various studies demonstrating the efficiency of LTX-315 therapy in inducing cancer cell death, the effects on cell cycle progression of this antitumoral peptide are poorly understood. In this research, we present data about the effect of LTX-315 on the cell cycle of two skin cancer cell lines: epidermoid carcinoma cells (A431) and melano

SUBMITTER: Santa-Gonzalez GA 

PROVIDER: S-EPMC7118296 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature