Long-Term Neurobehavioral and Quality of Life Outcomes of Critically Ill Children after Glycemic Control.

ABSTRACT:

Objectives

To investigate adaptive skills, behavior, and quality health-related quality of life in children from 32 centers enrolling in the Heart And Lung Failure-Pediatric INsulin Titration randomized controlled trial.

Study design

This prospective longitudinal cohort study compared the effect of 2 tight glycemic control ranges (lower target, 80-100 mg/dL vs higher target, 150-180 mg/dL) 1-year neurobehavioral and health-related quality of life outcomes. Subjects had confirmed hyperglycemia and cardiac and/or respiratory failure. Patients aged 2-16 years old enrolled between April 2012 and September 2016 were studied at 1 year after intensive care discharge. The primary outcome, adaptive skills, was assessed using the Vineland Adaptive Behavior Scale. Behavior and health-r

SUBMITTER: Biagas KV 

PROVIDER: S-EPMC7122648 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature