Frailty transitions and associated clinical outcomes in patients with stable COPD: A longitudinal study.

ABSTRACT:

Background

Although frailty is a frequent occurrence in chronic obstructive pulmonary disease (COPD) patients, evidence on the frequency of frailty transition is scarce.

Aims

The present study aimed to describe the frailty status transition rates over a 2-year period and their associated clinical outcomes in stable COPD patients, and to determine predictors of improvement in frailty status.

Methods

We prospectively included 119 patients with stable COPD (mean age ± SD, 66.9 ± 7.9 years) over a follow-up period of 2 years. Frailty was assessed using the Fried criteria (unintentional weight loss, weakness, exhaustion, low activity level, and slow walking speed). Several demographic, clinical, and health-related variables were measured. We calculated the rates for each o

SUBMITTER: Bernabeu-Mora R 

PROVIDER: S-EPMC7122798 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature