Blastulation of a zygote to a hatched blastocyst without any clear cell division: an observational finding in a time-lapse system after in vitro fertilization.

ABSTRACT:

Purpose

To describe an interesting not previously described morphokinetic finding.

Methods

Retrospective case report of a couple undergoing controlled ovarian stimulation (COS) followed by in vitro fertilization and blastocyst transfer.

Results

We identified a unique finding of blastulation of a fertilized human zygote after conventional in vitro fertilization. The fertilized zygote did not show any clear cytokinesis until approximately 107 h post insemination, when it started dividing into a blastocyst. By 113 h post insemination, inner cell mass and trophectoderm cells could be clearly distinguished and the blastocyst was completely hatched by 136 h post insemination.

Conclusion

Time-lapse systems offer more detailed observations of embryonic development. Her

SUBMITTER: Sandi-Monroy NL 

PROVIDER: S-EPMC7125290 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature