Mild proteasomal stress improves photosynthetic performance in Arabidopsis chloroplasts.

ABSTRACT: The proteasome is an essential protein-degradation machinery in eukaryotic cells that controls protein turnover and thereby the biogenesis and function of cell organelles. Chloroplasts import thousands of nuclear-encoded precursor proteins from the cytosol, suggesting that the bulk of plastid proteins is transiently exposed to the cytosolic proteasome complex. Therefore, there is a cytosolic equilibrium between chloroplast precursor protein import and proteasomal degradation. We show here that a shift in this equilibrium, induced by mild genetic proteasome impairment, results in elevated precursor protein abundance in the cytosol and significantly increased accumulation of functional photosynthetic complexes in protein import-deficient chloroplasts. Importantly, a proteasome lid mutant sho

SUBMITTER: Grimmer J 

PROVIDER: S-EPMC7125294 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature