MRNA cap-1 methyltransferase in the SARS genome.

ABSTRACT: The 3D jury system has predicted the methyltransferase fold for the nsp13 protein of the SARS coronavirus. Based on the conservation of a characteristic tetrad of residues, the mRNA cap-1 methyltransferase function has been assigned to this protein, which has potential implications for antiviral therapy.

SUBMITTER: von Grotthuss M 

PROVIDER: S-EPMC7126025 | biostudies-literature | 2003 Jun

REPOSITORIES: biostudies-literature