Arch-shaped multiple-target sensing for rapid diagnosis and identification of emerging infectious pathogens.

ABSTRACT: Rapid identification of emerging infectious pathogens is crucial for preventing public health threats. Various pathogen detection techniques have been introduced; however, most techniques are time-consuming and lack multiple-target detection specificity. Although multiple-target detection techniques can distinguish emerging infectious pathogens from related pathogens, direct amplification methods have not been widely examined. Here, we present a novel arch-shaped multiple-target sensor capable of rapid pathogen identification using direct amplification in clinical samples. In this study, an arch-shaped amplification containing primer sequences was designed to rapidly amplify multiple targets. Further, the sensing platform allowed for sensitive and specific detection of human coronavirus, M

SUBMITTER: Koo B 

PROVIDER: S-EPMC7126750 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature