A simple and compact smartphone-based device for the quantitative readout of colloidal gold lateral flow immunoassay strips.

ABSTRACT: Colloidal gold lateral flow immunoassay strips (AuNPs-LFIS) have been widely applied as qualitative diagnostic tools for point-of-care tests (POCT). If strip readers were incorporated, their use could be extended to quantitative analysis. However, their cost and non-portability render commercial strip readers unavailable for use in either home testing, community or rural hospital diagnosis. This is particularly true for on-site testing. Here, a smartphone-based reader was designed and 3D-printed for quantitatively assess AuNPs-LFIS. The basic principle of the devise was relying on a smartphone's ambient light sensor (SPALS). This sensor was harnessed to measure the transmitted light intensities originating from the T-lines on the strips, the transmitted light intensities vary with concentr

SUBMITTER: Xiao W 

PROVIDER: S-EPMC7127147 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature